![]() ![]() Based on parametric cure modelling, persistent self-reported smell and taste dysfunction could develop in an estimated 5.6% (95% confidence interval 2.7% to 11.0%, I 2=70%, τ 2=0.756, 95% prediction interval 0.7% to 33.5%) and 4.4% (1.2% to 14.6%, I 2=67%, τ 2=0.684, 95% prediction interval 0.0% to 49.0%) of patients, respectively. Risk of bias was low to moderate conclusions remained unaltered after exclusion of four high risk studies. Results 18 studies (3699 patients) from 4180 records were included in reconstructed IPD meta-analyses. 11Department of Otorhinolaryngology-Head and Neck Surgery, Guy’s and St Thomas’ Hospitals, London, UK.10Edge Hill University Medical School, Orsmkirk, UK.9Wigan and Leigh Teaching NHS Foundation Trust, Wrightington, UK.8Department of Physiology and Cell Biology, School of Medicine, University of Nevada, Reno, NV, USA.7Department of Molecular Cell Genetics, L Rydygier Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.6Department of Otorhinolaryngology-Head and Neck Surgery, Vanderbilt University Medical Centre, Nashville, TN, USA.5Department of Otorhinolaryngology-Head and Neck Surgery, Sengkang General Hospital, Singapore.4Department of Otorhinolaryngology-Head and Neck Surgery, Singapore General Hospital, Singapore.3Surgery Academic Clinical Program, SingHealth, Singapore.2Biostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. ![]() 1Yong Loo Lin School of Medicine, National University of Singapore, Singapore.Song Tar Toh, associate professor of otolaryngology 3 4.Claire Hopkins, professor of rhinology 11 12,.B Nirmal Kumar, professor of otolaryngology 9 10,. ![]()
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